Application guidance

Tank Mixing MetaGrow Microbes with Fertilizers, Fungicides and Pesticides

MetaGrow microbes are durable. While in stasis, they can be mixed with most ag chemicals — with a few important rules.

What it covers
Why microbes in stasis survive chemical mixes, when microbe food can be added, synthetic fertilizer mixing results, how to jar test a mix, and a compatibility list for common fungicides and pesticides.
Why it matters
Feeding microbes before chemical mixing — or holding a fed mix too long — wakes them up and leaves them vulnerable to the chemicals.
Who it’s for
Growers, applicators and pest control advisers planning tank mixes that combine MetaGrow with fertilizers, fungicides or pesticides.
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Timing at a glance

When this applies

Any time MetaGrow is combined with fertilizers, microbe food, fungicides or pesticides in the same tank.

When to make the decision

Jar test 2 to 3 days before the production mix. Apply mixes containing microbe food within 8 hours, and fungicide or pesticide mixes within 24 hours (preferably less than 8).

What it’s designed to support

Microbes that stay protected in stasis until they reach the field.

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MetaGrow microbes are durable

Microbes in stasis (all MetaGrow products) are protected from high temperatures (up to 120°F), freezing, high osmotic pressures, extreme pH, caustic materials and chemical toxicities. MetaGrow microbe products can be mixed with most ag chemicals while in stasis.

Actively respiring microbe products — those with a short shelf life or that require refrigeration — do not have protective coatings and suffer high mortality if mixed with synthetic fertilizers.

Microbes in stasis wake up

When food and habitat conditions are suitable, microbes in stasis wake up very quickly. If mixing microbes with microbe food or organic fertilizers, the mixture must be applied within 24 hours (preferably within 8 hours), as the microbes will wake up with exposure to food.

Synthetic fertilizer mixing

Synthetic fertilizers are typically not suitable habitat for microbes — they are too extreme in pH, caustic, high in osmotic pressure or toxic — so the microbes stay in their protective stasis.

95–100%MetaGrow survival in synthetic fertilizer mixes, with storage durations over a year
90–100%Mortality of actively respiring (non-stasis) microbe products mixed with synthetic fertilizers

Some successful fertilizer mixes tested at 50% concentrations include UN32, 8-4-10, 10-34-0 and K thiosulfate.

Jar test mixes first

  1. Mirror the production mix

    Use the same mixing order and concentrations as the intended production mix.

  2. Seal it for 2 to 3 days

    Let the mix sit in a sealed plastic bottle for 2 to 3 days at room temperature.

  3. Check for swelling or odor

    If the plastic bottle becomes swollen from off-gassing or has a bad smell, the test indicates the microbes woke up and are no longer stable.

  4. Test viability

    If the bottle is not swollen, do a further test to determine whether the microbes are still viable: dilute the mixture with water 10:1, feed with MFOOD™ or fish hydrolysate, stir and leave the top open.

  5. Look under a microscope

    After 24 hours, evaluate the microbes under a microscope. If the microbes are active, the mix is successful. If they are ruptured or inactive, they are incompatible.

Fungicides and pesticides

Most foliar-applied fungicides and pesticides (not systemic ones) have only minor effects on soil microbes. Do not tank mix more than 24 hours prior to application (preferably less than 8 hours).

MetaGrow tank-mix compatibility list

MetaGrow microbial tank-mix compatibility
Common nameTrade nameCompatibility
AzoxystrobinHeritage, QuadrisOK
BanrotBanrotAvoid combination
BenodamilBayletonAvoid combination
BenomylBenlateAvoid combination
Boscalid, 3-pyridinecarboxamide, 2-chloro-N-(4'-chloro(1,1'biphenyl)-2-yl)EnduraOK
CaptanCaptan, OrthocideAvoid combination
Carboxin + thiramVitavaxOK
ChloronebTerraneb SP, Terremec SP+B14Avoid combination
ChlorothalonilBravo Plus, Chloroflo, Chlortosip, Chloronil, Daconil 2787, Daconil Ultrex, StrikeOK
Chromobacterium subtsugaeGrandevoOK
Copper hydroxideKocideOK
Cydia pomonella granulovirusCYD-X HPOK
CyproconazoleSentinelOK
Difenoconazole + metalaxylDividendOK
DithiocarbamatesFerbamAvoid combination
Ethylenebisdithiocarbamate ion (EBDC) (C4H6N2S4)Powerline MZOK
EtridiazoleKobanAvoid combination
FenaminosulfLesanAvoid combination
FenarimolRubiganOK
FenpropathrinDanitolOK
Fludioxonil, 70 - N-[3-(1-methylethoxy) phenyl]-2-(trifluoromethyl) benzamideMaxim 4F, Maxim MZOK
FolpetPhaltan, Cleary’s 3336, Fungo, Systec 1998, Senator WSBAvoid combination
Fosetyl-ALAlliette, Prodigy, Alliette SignatureOK
HymexazolTachigarenOK
ImazalilFreshgard, Fungaflor, NuzoneAvoid combination
IprodioneRovral, Chipco 26019OK for bacteria, not for Myco
Mancozeb (EBDC)Manzate, Manzate flowable, Fore, Nubark MZ, Ridomil, Tops MZ, Tops MZ GAUCHOAvoid combination
Maneb (EBDC)Maneb, MancozebAvoid combination
Metalaxyl-RidomilApron / Subdue MaxxOK
MyclobutanilEagle, Rally, SysthaneOK
OlpisanOlpisanAvoid combination
OxyquinoleineCarbostyrilAvoid combination
PentchloronitrobenzeneBlockerAvoid combination
PropamocarbBanol, Previcur, ProplantOK
PropiconazoleStratego, Banner MAXXAvoid combination
PyraclostrobinHeadlineOK
PyrethroidLambdastar, DelegateAvoid combination
QuintozenePCNB Terrachlor, TurfcideAvoid combination
SpinosadEntrustOK
TebuconazoleFolicur®, Folicur 3.6Avoid combination
Tebuconazole + metalaxylRaxil XTAvoid combination
Tebuconazole + thiramRaxil ThiramAvoid combination
ThiazoleBenomyl, Benlate, Tersan 1991Avoid combination
ThiramThiram, Tersan 75Avoid combination
TriadimefonBayletonAvoid combination
Triflumizole—Avoid combination
Zinc ethylene bisdithiocarbamateDithaneOK
Zinc whiteZinc oxideAvoid combination
ZiramZiramAvoid combination

If you have questions regarding other chemical compatibilities, call SGS at (916) 284-9706 and we can figure it out.

Key takeaways

  • MetaGrow microbes in stasis survive most ag chemical mixes; actively respiring microbe products do not.
  • Never feed microbes before chemical mixing. Fed tank mixes with compatible chemicals should be applied within 8 hours.
  • MetaGrow showed 95–100% survival in synthetic fertilizer mixes such as UN32, 8-4-10, 10-34-0 and K thiosulfate.
  • Jar test every new mix for 2 to 3 days, then confirm viability under a microscope.
  • Check the compatibility list — several common fungicides should not be combined with MetaGrow.
Original SGS resource

Ag Chemical Tank Mix Compatibilities

This page is adapted from the SGS PDF “Ag Chemical Tank Mix Compatibilities” (© 2020), which remains the technical reference. The 3-page original is available to download, print and share.

View the Technical PDF (PDF, opens in a new tab)

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